R. J. Singh, D. K. Singh, "Syntheses, Characterization and Biological Activity of Some 1, 2, 4-Triazole Derivatives", Journal of Chemistry, vol. 6, Article ID 419214, 5 pages, 2009. https://doi.org/10.1155/2009/419214
Syntheses, Characterization and Biological Activity of Some 1, 2, 4-Triazole Derivatives
Syntheses of a series of 3-alkyl-4- amino-5- cyanomethyl-4H-1, 2, 4-triazoles with active methylene groups are described. The newly synthesized compounds were characterized by spectral and elemental analyses. Some compounds were screened for their antibacterial activity against S. aureus, E. coli, B. subtilis and P. aeruginosa. All the compounds carrying 1, 2, 4- triazole moiety showed significant biological activity.
Copyright © 2009 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.