Journal of Chemistry

Journal of Chemistry / 2009 / Article

Open Access

Volume 6 |Article ID 472530 |

Arjun K. Rana, Nayan R. Parekh, Harish R. Dabhi, Sunil S. Nadkarni, "Novel Synthesis and Characterization of Thiosemicarbazone Compounds Containing 4-Acyl-2-pyrazolin-5-ones", Journal of Chemistry, vol. 6, Article ID 472530, 6 pages, 2009.

Novel Synthesis and Characterization of Thiosemicarbazone Compounds Containing 4-Acyl-2-pyrazolin-5-ones

Received09 Oct 2008
Revised21 Dec 2008
Accepted15 Jan 2009


A novel synthesis of 4-acylthiosemicarbazone-3-methyl-1-(4`-methylphenyl)-2-pyrazolin-5-one by condensation of 4-acyl-3-methyl-1-(4`-methylphenyl)-2-pyrazolin-5-one with thiosemicarbazide is carried out. The compounds were characterized on the basis of elemental analysis, IR, 1H NMR, Mass, DSC and 13C NMR spectral data. The structures were investigated for their antibacterial and antifungal activity. They are very essential to study on cerebral infarction (Free radical scavenger). A single crystal X-ray study of this thiosemicarbazones and their metal complexes is in progress.

Copyright © 2009 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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