Journal of Chemistry

Journal of Chemistry / 2009 / Article

Open Access

Volume 6 |Article ID 535643 | 5 pages |

In Vitro Antimicrobial Screening of Alkaloid Fractions from Strychnos potatorum

Received03 Dec 2008
Revised08 Mar 2009
Accepted20 Mar 2009


Alkaloid fractions isolated from Strychnos potatorum L.f. (Loganiaceae) seed were tested for their antimicrobial properties against some pathogenic gram positive, gram negative and acid-fast bacteria and fungi. These fractions have shown considerable antimicrobial activity against both bacteria and fungi at the tested concentrations (100 & 200 μg/mL). Further, the growth of Proteus vulgaris, taphylococcus aureus, Salmonella typhimurium, Vibrio cholerae, Mycobacterium tuberculosis, Aspergillus niger and Candida albicans were significantly inhibited. These findings have confirmed the use of this plant in treating of several microbial infections both in traditional and folk medicine in India.

Copyright © 2009 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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