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E-Journal of Chemistry
Volume 6, Issue 1, Pages 39-46
http://dx.doi.org/10.1155/2009/583480

Design of New Electrode Interface to Improve Transport of Atmospheric Pressure Ions into a Mass Spectrometer

Francis Beaudry1 and Robert B. Moore1,2

1Department of Veterinary Medicine, Faculty of Veterinary Medicine, Groupe de Recherche en Pharmacologie Animal du Québec (GREPAQ), University of Montréal, St-Hyacinthe, Québec, Canada
2Department of Physics, McGill University, Montreal, Canada

Received 7 May 2008; Accepted 5 June 2008

Copyright © 2009 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

An intermediate electrode was developed to improve the transfer of ions in atmospheric pressure from a first location, the ion source, to a second location, the mass spectrometer. The new apparatus increase the efficiency of mass analysis of molecular constituents of liquids, including trace analysis of chemical entities, in which an electrospray (ES) or IonSpray™ (IS) technique is used to produce electrically charged droplets which divide and evaporate to form gaseous ions of the molecular constituents. The gas phase ions are transported to the mass spectrometer by an electric field generated by a new electrode design that separates the two fundamental functions of an electrospray or an IonSpray™, which are the nebulization of charged droplets and the transport of ions into the mass analyzer. The results suggest that the new apparatus provide a gain in signal intensity up to 10 compared with the commercial product. A significant improvement in ion transport results in higher precision and accuracy and/or reduction of the amount of material needed for analysis.