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Synthesis, Characterization and Antibacterial Activity of Mn(II), Co(II), Ni(II) and Cu(II) Complexes of 4-Carboxaldehyde Phenylhydrazone- 1-phenyl-3-methyl-2-pyrazolin-5-one
R. N. Pandya,1 A. K. Rana,2 H. R. Dabhi
,2 R. B. Patel,3 D. K. Bhoi,4 M. B. Patel,1 K. S. Solanki,5 R. K. Rai,2 and A. D. Raj21Sheth P. T. Arts & Science College, Godhra-389 001, India
2Navjivan Science College, Dahod-389151, India
3J.B. Pharmaceutical, Ankleshwar, India
4J & J Science College, Nadiad, India
5Cadila Pharmaceutical, Ahmedabad, India
Abstract
4-Carboxaldehyde-1-phenyl-3-methyl-2-pyrazolin-5-one condensed with phenylhydrazine to form ligand (HL). These metal complexes are of type [ML2 (H2O)2] (M = Mn, Co, Ni and Cu). Elemental analysis, magnetic susceptibility, electrical conductance, electronic and infrared data suggest octahedral structure for the metal complexes. All the compounds were tested for their antibacterial activity. The result indicates that the growth of the tested organisms was inhibited by most of the compounds.
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Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
