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E-Journal of Chemistry
Volume 7, Issue 3, Pages 1029-1032
http://dx.doi.org/10.1155/2010/576150

Evaluation of Haematological and Immunological Status in Type 2 Diabetics

A. Sohna Chandra Packiavathy1 and M. Ramalingam2

1Department of Biochemistry, PRIST University, Thanjavur-614904, India
2Center for Research and Development, PRIST University, Vallam, Thanjavur-613103, India

Received 20 October 2009; Accepted 15 December 2009

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Type 2 diabetes is a heterogeneous disorder involving impairment of both insulin secretion and insulin action. The immunological and haematological statuses during normal and diseased conditions have been studied. The study groups consisted of 220 patients (110 males, 110 females) and 220 age and sex matched control subjects (110 males, 110 females). The values of IgG, IgM, IgE and IgA were found to be significantly increased. Leucocyte count and erythrocyte sedimentation rate were also found to be increased in the type 2 diabetics as compared to controls. The study suggests that variation in the levels of immunoglobulins and cell count may be involved in the pathogenesis of type 2 diabetes mellitus.