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E-Journal of Chemistry
Volume 7, Issue 4, Pages 1584-1590
http://dx.doi.org/10.1155/2010/759497

Isolation, Characterization and Anti-Inflammatory Property of Thevetia Peruviana

R. Thilagavathi,2 Helen P. Kavitha,1 and B. R. Venkatraman2

1Department of Chemistry, SRM University, Ramapuram, Chennai-89, India
2Department of Chemistry, Periyar E.V.R College, Trichirappalli-23, Tamilnadu, India

Received 2 October 2009; Revised 3 March 2010; Accepted 1 May 2010

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Thevetia peruviana seeds contain glucosides of neriifolin, acetylneriifolin and thevetin. Seed oil distillates of Thevetia peruviana have been found to contain anti-bacterial activity. In the persent work, the fresh flowers of Thevetia peruviana was subjected to phytochemical studies. The results of the study showed that the flowers contain quercetin, kaempferol and quercetin-7-o-galactoside. The structure of the isolated compound was characterized by UV, 1H NMR and 13C NMR spectra. The anti-inflammatory character of the isolated compound was tested by in vitro method and the results of the study revealed that the isolated compound showed a biphasic property.