Journal of Chemistry

Journal of Chemistry / 2010 / Article

Open Access

Volume 7 |Article ID 769137 |

Milan Ch. Dutta, Kaushik Chanda, R. L. Nongkhlaw, Jai N. Vishwakarma, "A Facile Microwave Assisted One-pot Strategy for the Synthesis of Bis-hexahydroquinazolin-5(6H)-ones", Journal of Chemistry, vol. 7, Article ID 769137, 6 pages, 2010.

A Facile Microwave Assisted One-pot Strategy for the Synthesis of Bis-hexahydroquinazolin-5(6H)-ones

Received15 Jun 2009
Accepted18 Jul 2009


A facile microwave assisted one-pot synthetic protocol has been devised for the synthesis of 3,3'-(alkanediyl) bis (1-phenyl-1,2,3,4,7,8-hexahydroquinazolin-5(6H)-ones (2a-c), 3,3'-(1,4-phenylene) bis (1-phenyl-1,2,3,4,7,8-hexahydroquinazolin-5(6H)-one (2d),3,3'-(alkanediyl) bis (7,7-dimethyl-1-phenyl-1,2,3,4,7,8-hexahydroquinazolin-5(6H)-ones (2e-g) and 3,3'-(1,4-phenylene) bis(7,7-dimethyl-1-phenyl-1,2,3,4,7,8-hexahydroquinazolin-5(6H)-one (2h) by the cyclocondensation of cyclic enaminones 1a, b with diamines and formaldehyde.

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