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Milan Ch. Dutta, Kaushik Chanda, R. L. Nongkhlaw, Jai N. Vishwakarma, "A Facile Microwave Assisted One-pot Strategy for the Synthesis of Bis-hexahydroquinazolin-5(6H)-ones", Journal of Chemistry, vol. 7, Article ID 769137, 6 pages, 2010. https://doi.org/10.1155/2010/769137
A Facile Microwave Assisted One-pot Strategy for the Synthesis of Bis-hexahydroquinazolin-5(6H)-ones
Abstract
A facile microwave assisted one-pot synthetic protocol has been devised for the synthesis of 3,3'-(alkanediyl) bis (1-phenyl-1,2,3,4,7,8-hexahydroquinazolin-5(6H)-ones (2a-c), 3,3'-(1,4-phenylene) bis (1-phenyl-1,2,3,4,7,8-hexahydroquinazolin-5(6H)-one (2d),3,3'-(alkanediyl) bis (7,7-dimethyl-1-phenyl-1,2,3,4,7,8-hexahydroquinazolin-5(6H)-ones (2e-g) and 3,3'-(1,4-phenylene) bis(7,7-dimethyl-1-phenyl-1,2,3,4,7,8-hexahydroquinazolin-5(6H)-one (2h) by the cyclocondensation of cyclic enaminones 1a, b with diamines and formaldehyde.
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Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
