Journal of Chemistry

Journal of Chemistry / 2010 / Article

Open Access

Volume 7 |Article ID 904205 | 7 pages |

Synthesis, Characterisation, Spectral and Microbial Studies of Transition Metal Complexes of the Drug, Secnidazole

Received20 Feb 2010
Accepted01 May 2010


5-Chloromethyl-8-quinolinol hydrochloride was condensed with 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol in presence of potassium carbonate. The resulting 5-((1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-yloxy)methyl)quinolin-8-ol was characterized by elemental analysis and spectral studies. The transition metal chelates of the same were prepared with Cu2+, Ni2+, Co2+, Mn2+ and Zn2+ and characterized by IR and electronic spectral studies and magnetic properties. The antimicrobial activity of ligand and its metal chelates were screened against various gram positive and gram negative organisms. The results show that all these samples are more or less active agents against various organisms.

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

More related articles

468 Views | 979 Downloads | 3 Citations
 PDF  Download Citation  Citation
 Order printed copiesOrder

Related articles

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.