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E-Journal of Chemistry
Volume 8 (2011), Issue 1, Pages 231-239
http://dx.doi.org/10.1155/2011/214870

Synthesis, Spectroscopic Characterization and Preliminary Antimicrobial Studies of Mn(II) and Cu(II) Complexes of two Thiolates; S,S’-(2,6-Diaminopyridine-3,5-diyl) Dibenzenecarbothioate (DBCT) and S-Benzyl Benzenecarbothioate (BBCT)

P. O. Ukoha,1 C.U. Alioke,1 N.L> Obasi,1 and K.F. Chah2

1Department of Pure and Industrial Chemistry, University of Nigeria, Nsukka, Enugu State, Nigeria
2Department of Veterinary Physiology and Parasitology, University of Nigeria, Nsukka, Enugu State, Nigeria

Received 9 December 2009; Revised 11 March 2010; Accepted 19 March 2010

Copyright © 2011 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

S,S’-(2,6-Diaminopyridine-3,5-diyl)dibenzenecarbothioate was formed by condensing 2,6-diamino-3,5-dithiopyridine and benzoyl chloride in the presence of pyridine. Also S-benzyl benzenecarbothioate was prepared by the condensation of benzoyl chloride and phenylmethanethiol in the presence of pyridine. The complexes of these compounds were prepared using copper(II) and manganese(II) chloride salts. The thiolates were characterized on the basis of their electronic, infrared and NMR spectra whereas the complexes were characterized via electronic and infrared studies. The IR spectral studies indicate that the ligands coordinated through the carbonyl oxygen, the sulphur atom and also with the amino group in DBCT. Antimicrobial studies on the ligands and their complexes showed varying degrees of inhibition on the growth of the following microorganisms; Staphylococcus aureus (ATCC 25923), Pseudomonas aeruginosa (ATCC 27853), Bacillus subtilis (ATCC 6633) and Candida albicans (ATCC 2091). The compounds showed no activity against Escherichia coli (ATCC 25922)