Journal of Chemistry

Journal of Chemistry / 2011 / Article

Open Access

Volume 8 |Article ID 545403 |

P. Rashmi, Gopal Krishna Rao, Kshama Devi, B. G. Shivananda, G. R. Swetha, G. A. Suneetha, "Novel Aryl Ether Derivatives as Antiinflammatory and Analgesics", Journal of Chemistry, vol. 8, Article ID 545403, 7 pages, 2011.

Novel Aryl Ether Derivatives as Antiinflammatory and Analgesics

Received26 Sep 2010
Accepted27 Nov 2010


The diaryl ether moieties have attracted considerable attention of medicinal chemists as they are endowed with a wide range of diverse biological activities. The present study involves synthesis, characterization of some new aryl ethers and evaluation of their antiinflammatory and analgesic activity. A series of new aryl ether derivatives [4(a-h), 5] were prepared by Ullmann’s ether condensation. The structures of new compounds are supported by their IR, 1H NMR and Mass spectra. The new derivatives were evaluated for their antiinflammatory and analgesic activity. Among the tested, compound 3 has shown better antiinflammatory and analgesic activity.

Copyright © 2011 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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