Journal of Chemistry

Journal of Chemistry / 2011 / Article

Open Access

Volume 8 |Article ID 545403 | https://doi.org/10.1155/2011/545403

P. Rashmi, Gopal Krishna Rao, Kshama Devi, B. G. Shivananda, G. R. Swetha, G. A. Suneetha, "Novel Aryl Ether Derivatives as Antiinflammatory and Analgesics", Journal of Chemistry, vol. 8, Article ID 545403, 7 pages, 2011. https://doi.org/10.1155/2011/545403

Novel Aryl Ether Derivatives as Antiinflammatory and Analgesics

Received26 Sep 2010
Accepted27 Nov 2010

Abstract

The diaryl ether moieties have attracted considerable attention of medicinal chemists as they are endowed with a wide range of diverse biological activities. The present study involves synthesis, characterization of some new aryl ethers and evaluation of their antiinflammatory and analgesic activity. A series of new aryl ether derivatives [4(a-h), 5] were prepared by Ullmann’s ether condensation. The structures of new compounds are supported by their IR, 1H NMR and Mass spectra. The new derivatives were evaluated for their antiinflammatory and analgesic activity. Among the tested, compound 3 has shown better antiinflammatory and analgesic activity.

Copyright © 2011 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


More related articles

 PDF Download Citation Citation
 Order printed copiesOrder
Views435
Downloads659
Citations

Related articles

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.