Journal of Chemistry

Journal of Chemistry / 2012 / Article

Open Access

Volume 9 |Article ID 165784 | 7 pages | https://doi.org/10.1155/2012/165784

Synthesis of Novel N1 and N2 Indazole Derivatives

Received21 Aug 2011
Accepted27 Oct 2011

Abstract

The alkylation of 5-cyano indazoles 2 in the presence of readily available imidizolium salts (ionic liquids) (Bmim)BF4 as phase transfer catalyst were performed to afford the regio isomers N1-and N2-(substituted alkyl)-5-cyano indazoles. The N1-alkylated cyano indazoles were converted to the corresponding N1-(substituted alkyl)-5-aminomethyl and 5-carbaldehydes 5(a-f) and 6(a-f).

Copyright © 2012 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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