Prasanna Bethanamudi, Srinivas Bandari, Kanakaraju Sankari, Amarnath Velidandi, G. V. P. Chandramouli, "Synthesis of Novel N1 and N2 Indazole Derivatives", Journal of Chemistry, vol. 9, Article ID 165784, 7 pages, 2012. https://doi.org/10.1155/2012/165784
Synthesis of Novel N1 and N2 Indazole Derivatives
The alkylation of 5-cyano indazoles 2 in the presence of readily available imidizolium salts (ionic liquids) (Bmim)BF4 as phase transfer catalyst were performed to afford the regio isomers N1-and N2-(substituted alkyl)-5-cyano indazoles. The N1-alkylated cyano indazoles were converted to the corresponding N1-(substituted alkyl)-5-aminomethyl and 5-carbaldehydes 5(a-f) and 6(a-f).
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