PDF
Open Access
CdTe Quantum dots Modified by Polyamidoamine Dendrimers for Cell Imaging
Jun'An Liu,1 Xiaolei Wei,1 Jianhua Cao,2 and Hong Jiang
11College of Science, Huazhong Agricultural University, Wuhan-430070, China
2College of Animal Sciences & Technology/College of Veterinary Medicine, Huazhong Agricultural University, Wuhan-430070, China
Abstract
Water soluble CdTe quantum dots have shown potential as a platform for development of live cell imaging, but their cytotoxicity limits their biological applications. To decrease their cytotoxicity, an approach to modify CdTe quantum dots (QDs) with polyamidoamine (PAMAM) was employed by forming covalent bonds between them. The resultant nanocomposites as a cell imaging bioprobe for live PK15 and their in vitro toxicity were also investigated. The results showed that the prepared nanocomposites were able to enter PK15 cells with good biocompatibility and low cellular toxicity.
Copyright
Copyright © 2012 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
