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E-Journal of Chemistry
Volume 9, Issue 2, Pages 504-509

An Efficient One-Pot Synthesis of 1,8-Dioxodecahydroacridines Using Silica-Supported Polyphosphoric Acid (PPA-SiO2) under Solvent-Free Conditions

1Department of Chemistry, Islamic Azad University - Bandar Abbas Branch, Bandar Abbas 7915893144, Iran
2Department of Chemistry, Islamic Azad University - Mashhad Branch, Mashhad, Iran

Received 28 May 2011; Accepted 5 August 2011

Copyright © 2012 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Silica gel–supported polyphosphoric acid (PPA-SiO2) was found to be an efficient catalyst for the synthesis of 1,8-dioxodecahydroacridines via one-pot three-component condensation of aryl aldehydes, dimedone, and ammonium acetate or 4-methyl aniline in high yields, easy workup procedure and short period of times. The catalyst was separated by simple filtration and used in the reaction three times without any significant loss of its activity.