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E-Journal of Chemistry
Volume 9, Issue 2, Pages 739-743

Zr(HSO4)4: An Efficient Catalyst for the Synthesis of 3-(2'- Benzothiazolyl)-2,3-dihydroquinazolin- 4(1H)-ones

School of Pharmacy, Xinxiang Medical University, Xinxiang, Henan 453003, China

Received 29 August 2011; Accepted 27 October 2011

Copyright © 2012 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A simple and efficient synthesis of 3-(2'-benzothiazolyl)-2,3-dihydro quinazolin-4(1H)- ones has been accomplished by the one-pot condensation of isatoic anhydride, aldehyde and 2-aminobenzothiazole under solvent-free conditions in the presence of Zr(HSO4)4.