An Efficient One-Pot Synthesis of 1, 5-Benzodiazepine Derivatives Catalyzed by TBAB under Mild Conditions

Baseer, Mohammad A.; Khan, Asgar Jafar

doi:https://doi.org/10.1155/2012/657439

Journal of Chemistry

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Volume 9 | Article ID 657439 | https://doi.org/10.1155/2012/657439

An Efficient One-Pot Synthesis of 1, 5-Benzodiazepine Derivatives Catalyzed by TBAB under Mild Conditions

Mohammad A. Baseer¹and Asgar Jafar Khan²

Received18 Jun 2010

Accepted01 Mar 2011

Abstract

2,3-Dihydro-1H-1,5-benzodiazepines were synthesized by reaction of o-phenylenediamine with ketones (acyclic / cyclic) under solvent free conditions in the presence of tetra butyl ammonium bromide (TBAB) in short reaction time with excellent yield.

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Copyright © 2012 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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