Hossein Anaraki-Ardakani, Maziar Noei, Mina Karbalaei-Harofteh, Shahab Zomorodbakhsh, "A Facile Synthesis of Polysubstituted Pyrroles by One-Pot Three-Component Reaction", Journal of Chemistry, vol. 9, Article ID 915861, 6 pages, 2012. https://doi.org/10.1155/2012/915861
A Facile Synthesis of Polysubstituted Pyrroles by One-Pot Three-Component Reaction
A new and efficient one-pot synthesis of polysubstituted pyrrole derivatives by three-component reaction between dialkyl acetylenedicarboxylates, triphenylphosphine, 2-aminopyridin derivatives in the presence of arylglyoxals is described. The reactions were performed in dichloromethane at room temperature and neutral conditions and afforded high yields of products.
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