“On Water” Sonochemical Multicomponent Synthesis of Novel Bioactive 1,1′-(Aryl)bis(2-(cyclohexylamino)-2-oxoethane-1,1-diyl) Di(alkanoates and benzoates)

Table 1

Effect of various solvents in the synthesis of 6a under ultrasonic irradiation.

Solvent	Time (min)	Yield (%)^a
DMF	80	30
CH2Cl2	85	25
1,4-Dioxane	95	25
H2O	4 (70)^b	90 (65)^b

aIsolated yields.
^bThe reaction at room temperature under conventional condition.