Journal of Chemistry
Volume 2013, Article ID 149270, 8 pages
http://dx.doi.org/10.1155/2013/149270
Exploration of Newer Possibilities to the Synthesis of Diazepine and Quinoline Carboxylic Acid Derivatives
Department of Chemistry, Banasthali University, Banasthali, Jaipur 304022, India
Received 3 February 2012; Revised 23 June 2012; Accepted 9 July 2012
Academic Editor: Casimiro Mantell
Copyright © 2013 Vatsala Soni et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Heterocyclic systems containing benzothiazoles, carbazole (and azacarbazole) moieties have attracted the attention of chemists owing to these nuclei having been identified in the literature as most promising pharmacophores in drug design and synthesis. Based on these observations, it could be anticipated that incorporation of the bioactive azepine moiety and quinoline moiety into the molecular framework of benzothiazoles fused to carbazole (and azacarbazoles) could produce interesting series of compounds 9–12 with enhanced biological activities, whose structure was unequivocally established from its microanalyses and spectral data.