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Journal of Chemistry
Volume 2013, Article ID 195074, 16 pages
http://dx.doi.org/10.1155/2013/195074
Research Article

Synthesis, Spectroscopic Characterisation, and Biopotential and DNA Cleavage Applications of Mixed Ligand 4-N,N-Dimethylaminopyridine Metal Complexes

1Anna University, BIT Campus, Tiruchirappalli, Tamil Nadu 620 024, India
2Saranathan College of Engineering, Panjappur, Tiruchirappalli 12, Tamil Nadu 620 012, India

Received 8 May 2013; Revised 23 August 2013; Accepted 29 August 2013

Academic Editor: Josefina Pons

Copyright © 2013 C. Surendra Dilip et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The mixed ligand transition metal complexes of 4-N,N-dimethylaminopyridine (DP) and chloride as primary and secondary ligands with the general formula [M(DP)3Cl3]; M = Cr(III) and Fe(III); [M′(DP)4Cl2]M′ = Co(II), Ni(II), Cu(II), and Cd(II) were synthesized in a microwave oven. The complexes were characterized by FT-IR and UV, 1HNMR, 13CNMR spectra, TG/DTG, and various physicoanalytical techniques. From the magnetic moment measurements and the electronic spectral data, a distorted octahedral geometry was proposed for the complexes. The complexes express similar trend of thermal behaviour such that they lose water of hydration initially with the subsequent emission of organic and inorganic fragments and leave left the metal oxides as residue. The activation thermodynamic parameters, such as , , , and of the metal complexes, illustrate the spontaneous formation of the complexes. The antimicrobial studies against various pathogenic bacterial and fungal serums insist on that the enhanced potential of the complexes over their ligand and their biopotential properties increases with concentration. The DNA interaction of the synthesized complexes on CT-DNA was investigated by UV-Vis spectroscopy, viscosity, thermal denaturation, and electroanalytical experiments and their binding constants ( ) were also calculated.