Research Article

Superparamagnetic Iron Oxide as an Efficient Catalyst for the One-Pot, Solvent-Free Synthesis of 5,5-Disubstituted Hexahydropyrimidines and Their Spiro Analogues

Scheme 3

Synthesis of bis-spiropiperidines using dimedone, aromatic amines, and formaldehyde.
214617.sch.003