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Journal of Chemistry
Volume 2013 (2013), Article ID 239342, 7 pages
http://dx.doi.org/10.1155/2013/239342
Research Article

A Simple HPLC-DAD Method for the Analysis of Melamine in Protein Supplements: Validation Using the Accuracy Profiles

Department of Pharmacy, University of Naples Federico II, Via D. Montesano 49, 80131 Naples, Italy

Received 7 May 2013; Accepted 15 July 2013

Academic Editor: Pranav S. Shrivastav

Copyright © 2013 Domenico Montesano et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. E. L. Bradley, V. Boughtflower, T. L. Smith, D. R. Speck, and L. Castle, “Survey of the migration of melamine and formaldehyde from melamine food contact articles available on the UK market,” Food Additives and Contaminants, vol. 22, no. 6, pp. 597–606, 2005. View at Publisher · View at Google Scholar · View at Scopus
  2. K. H. Lund and J. H. Petersen, “Migration of formaldehyde and melamine monomers from kitchen- and tableware made of melamine plastic,” Food Additives and Contaminants, vol. 23, no. 9, pp. 948–955, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. C.-Y. Chien, C.-F. Wu, C.-C. Liu et al., “High melamine migration in daily-use melamine-made tableware,” Journal of Hazardous Materials, vol. 188, no. 1-3, pp. 350–356, 2011. View at Publisher · View at Google Scholar · View at Scopus
  4. Z. Chik, D. E. Mohamad Haron, E. D. Ahmad, H. Taha, and A. M. Mustafa, “Analysis of melamine migration from melamine food contact articles,” Food Additives and Contaminants, vol. 28, no. 7, pp. 967–973, 2011. View at Publisher · View at Google Scholar · View at Scopus
  5. J. L. Dorne, D. R. Doerge, M. Vandenbroeck et al., “Recent advances in the risk assessment of melamine and cyanuric acid in animal feed,” Toxicology and Applied Pharmacology, vol. 270, no. 3, pp. 218–229, 2012. View at Publisher · View at Google Scholar · View at Scopus
  6. R. Reimschuessel, E. R. Evans, C. B. Stine et al., “Renal crystal formation after combined or sequential oral administration of melamine and cyanuric acid,” Food and Chemical Toxicology, vol. 48, no. 10, pp. 2898–2906, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. R. Reimschuessel and B. Puschner, “Melamine toxicity-stones vs. crystals,” Journal of Medical Toxicology, vol. 6, no. 4, pp. 468–469, 2010. View at Publisher · View at Google Scholar · View at Scopus
  8. US FDA (United States Federal and Drug Administration), Interim Safety and Risk Assessment of Melamine and Its Analogues in Food For Humans Silver Spring, United States Department of Health and Human Services, Food and Drug Administration Center for Food Safety and Applied Nutrition, 2008, http://www.fda.gov/ScienceResearch/SpecialTopics/PeerReviewofScientificInformationandAssessments/ucm155012.htm.
  9. WHO, Expert Meeting to Review Toxicological Aspects of Melamine and Cyanuric Acid by World Health Organization, 2008.
  10. WHO (World Health Organization), Toxicological and Health Aspects of Melamine and Cyanuric Acid, Report of a WHO Expert Meeting in Collaboration with FAO, 2009.
  11. R. L. M. Dobson, S. Motlagh, M. Quijano et al., “Identification and characterization of toxicity of contaminants in pet food leading to an outbreak of renal toxicity in cats and dogs,” Toxicological Sciences, vol. 106, no. 1, pp. 251–262, 2008. View at Publisher · View at Google Scholar · View at Scopus
  12. R. P. Dalal and D. S. Goldfarb, “Melamine-related kidney stones and renal toxicity,” Nature Reviews Nephrology, vol. 7, no. 5, pp. 267–274, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. E. Chan, S. Griffiths, and C. Chan, “Public-health risks of melamine in milk products,” The Lancet, vol. 372, no. 9648, pp. 1444–1445, 2008. View at Publisher · View at Google Scholar · View at Scopus
  14. J. R. Ingelfinger, “Melamine and the global implications of food contamination,” The New England Journal of Medicine, vol. 359, no. 26, pp. 2745–2748, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. W. H. Tolleson, “Intentional and unintentional contaminants in food and feed,” in American Chemical Society, F. Al-Taher, L. S. Jackson, and J. W. DeVries, Eds., p. 55, 2009. View at Google Scholar
  16. EFSA (European Food Safety Authority), “Risks for public health due to the presences of melamine in infant milk and other milk products in China,” EFSA Journal, vol. 807, pp. 1–10, 2008. View at Google Scholar
  17. U. S. FDA, Update: Interim a Safety and Risk Assessment of Melamine and Its Analogues in Food for Humans, United States Department of Health and Human Services, Food and Drug Administration Center for Food Safety and Applied Nutrition, 2008, http://www.fda.gov/Food/FoodborneIllnessContaminants/ChemicalContaminants/ucm164520.
  18. EFSA, “Scientific opinion on melamine in food and feed EFSA panel on contaminants in the food chain (CONTAM) and EFSA panel on food contact materials, enzymes, flavourings and processing aids (CEF),” EFSA Journal, vol. 8, no. 8, p. 1573, 2010. View at Google Scholar
  19. S. A. Tittlemier, “Methods for the analysis of melamine and related compounds in foods: a review,” Food Additives and Contaminants A, vol. 27, no. 2, pp. 129–145, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. A. Arnold, T. N. Arrey, M. Karas, and M. Persike, “Fast quantitative determination of melamine and its derivatives by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry,” Rapid Communications in Mass Spectrometry, vol. 25, no. 19, pp. 2844–2850, 2011. View at Publisher · View at Google Scholar · View at Scopus
  21. E. Braekevelt, B. P.-Y. Lau, S. Feng, C. Ménard, and S. A. Tittlemier, “Determination of melamine, ammeline, ammelide and cyanuric acid in infant formula purchased in Canada by liquid chromatography-tandem mass spectrometry,” Food Additives and Contaminants A, vol. 28, no. 6, pp. 698–704, 2011. View at Publisher · View at Google Scholar · View at Scopus
  22. Y.-Y. Chao, Y.-T. Wei, C.-T. Lee, H.-S. Kou, and Y.-L. Huang, “Membrane sampling with microdialysis coupled to HPLC/UV for on-line simultaneous determination of melamine and cyanuric acid in non-dairy coffee creamer,” Analytical Sciences, vol. 27, no. 10, pp. 1025–1030, 2011. View at Google Scholar · View at Scopus
  23. S. Goscinny, V. Hanot, J. F. Halbardier, J. Y. Michelet, and J. Van Loco, “Rapid analysis of melamine residue in milk, milk products, bakery goods and flour by ultra-performance liquid chromatography/tandem mass spectrometry: from food crisis to accreditation,” Food Control, vol. 22, no. 2, pp. 226–230, 2011. View at Publisher · View at Google Scholar · View at Scopus
  24. H. Sun, L. Wang, L. Ai, S. Liang, and H. Wu, “A sensitive and validated method for determination of melamine residue in liquid milk by reversed phase high-performance liquid chromatography with solid-phase extraction,” Food Control, vol. 21, no. 5, pp. 686–691, 2010. View at Publisher · View at Google Scholar · View at Scopus
  25. F. Sun, W. Ma, L. Xu et al., “Analytical methods and recent developments in the detection of melamine,” Trends in Analytical Chemistry, vol. 29, no. 11, pp. 1239–1249, 2010. View at Publisher · View at Google Scholar · View at Scopus
  26. H. Sun, X. Qin, X. Ge, and L. Wang, “Effective separation and sensitive determination of cyanuric acid, melamine and cyromazine in environmental water by reversed phase high-performance liquid chromatography,” Environmental Technology, vol. 32, no. 3, pp. 317–323, 2011. View at Publisher · View at Google Scholar · View at Scopus
  27. Y. B. Zhong, L. J. Zhang, H. C. Zhang, J. X. Liu, and J. P. Wang, “Immunoaffinity-based solid phase extraction for the determination of melamine in animal-derived foods followed by LC,” Chromatographia, vol. 73, no. 11-12, pp. 1211–1215, 2011. View at Publisher · View at Google Scholar · View at Scopus
  28. H. Zhu, S. Zhang, M. Li, Y. Shao, and Z. Zhu, “Electrochemical sensor for melamine based on its copper complex,” Chemical Communications, vol. 46, no. 13, pp. 2259–2261, 2010. View at Publisher · View at Google Scholar · View at Scopus
  29. Y. Cheng and Y. Dong, “Screening melamine contaminant in eggs with portable surface-enhanced Raman spectroscopy based on gold nanosubstrate,” Food Control, vol. 22, no. 5, pp. 685–689, 2011. View at Publisher · View at Google Scholar · View at Scopus
  30. R. M. Balabin and S. V. Smirnov, “Melamine detection by mid- and near-infrared (MIR/NIR) spectroscopy: a quick and sensitive method for dairy products analysis including liquid milk, infant formula, and milk powder,” Talanta, vol. 85, no. 1, pp. 562–568, 2011. View at Publisher · View at Google Scholar · View at Scopus
  31. J. Lee, E. Jeong Jeong, and J. Kim, “Selective and sensitive detection of melamine by intra/inter liposomal interaction of polydiacetylene liposomes,” Chemical Communications, vol. 47, no. 1, pp. 358–360, 2011. View at Publisher · View at Google Scholar · View at Scopus
  32. M. Zhangay, H. Pingay, X. Caoa et al., “Rapid determination of melamine in milk using water-soluble CdTe quantum dots as fluorescence probes,” Food Additives and Contaminants, vol. 29, no. 3, pp. 333–344, 2012. View at Google Scholar
  33. B. Beltrán-Martinavarro, J. Peris-Vicente, S. Marco-Peiró, J. Esteve-Romero, M. Rambla-Alegre, and S. Carda-Broch, “Use of micellar mobile phases for the chromatographic determination of melamine in dietetic supplements,” Analyst, vol. 137, no. 1, pp. 269–274, 2012. View at Publisher · View at Google Scholar · View at Scopus
  34. P. Araujo, “Key aspects of analytical method validation and linearity evaluation,” Journal of Chromatography B, vol. 877, no. 23, pp. 2224–2234, 2009. View at Publisher · View at Google Scholar · View at Scopus
  35. M. Feinberg, B. Boulanger, W. Dewé, and P. Hubert, “New advances in method validation and measurement uncertainty aimed at improving the quality of chemical data,” Analytical and Bioanalytical Chemistry, vol. 380, no. 3, pp. 502–514, 2004. View at Publisher · View at Google Scholar · View at Scopus
  36. M. Feinberg, “Validation of analytical methods based on accuracy profiles,” Journal of Chromatography A, vol. 1158, no. 1-2, pp. 174–183, 2007. View at Publisher · View at Google Scholar · View at Scopus
  37. P. Hubert, J. J. Nguyen-Huu, B. Boulanger et al., “Validation of quantitative analytical procedure, harmonization of approaches,” S.T.P. Pharma Pratiques, vol. 13, no. 3, pp. 101–138, 2003. View at Google Scholar · View at Scopus
  38. P. Hubert, J.-J. Nguyen-Huu, B. Boulanger et al., “Harmonization of strategies for the validation of quantitative analytical procedures: a SFSTP proposal—part I,” Journal of Pharmaceutical and Biomedical Analysis, vol. 36, no. 3, pp. 579–586, 2004. View at Publisher · View at Google Scholar · View at Scopus
  39. P. Hubert, J.-J. Nguyen-Huu, B. Boulanger et al., “Harmonization of strategies for the validation of quantitative analytical procedures. A SFSTP proposal—part III,” Journal of Pharmaceutical and Biomedical Analysis, vol. 45, no. 1, pp. 82–96, 2007. View at Publisher · View at Google Scholar · View at Scopus
  40. P. Hubert, J.-J. Nguyen-Huu, B. Boulanger et al., “Harmonization of strategies for the validation of quantitative analytical procedures: a SFSTP proposal. Part IV. Examples of application,” Journal of Pharmaceutical and Biomedical Analysis, vol. 48, no. 3, pp. 760–771, 2008. View at Publisher · View at Google Scholar · View at Scopus
  41. ISO/IEC, General Requirements for the Competence of Testing and Calibration Laboratories, ISO, Geneva, Switzerland, 2005.
  42. E. Rozet, V. Wascotte, N. Lecouturier et al., “Improvement of the decision efficiency of the accuracy profile by means of a desirability function for analytical methods validation. Application to a diacetyl-monoxime colorimetric assay used for the determination of urea in transdermal iontophoretic extracts,” Analytica Chimica Acta, vol. 591, no. 2, pp. 239–247, 2007. View at Publisher · View at Google Scholar · View at Scopus
  43. B. Boulanger, P. Chiap, W. Dewe, J. Crommen, and P. Hubert, “An analysis of the SFSTP guide on validation of chromatographic bioanalytical methods: progresses and limitations,” Journal of Pharmaceutical and Biomedical Analysis, vol. 32, no. 4-5, pp. 753–765, 2003. View at Publisher · View at Google Scholar · View at Scopus
  44. R. Mee, “Estimation of the percentage of a normal distribution lying outside a specified interval,” Communication in Statististics, vol. 17, no. 5, pp. 1465–1479, 1988. View at Google Scholar
  45. Analytical Methods Committee, “Uncertainty of measurement: implications of its use in analytical science,” Analyst, vol. 120, no. 9, pp. 2303–2306, 1995. View at Google Scholar
  46. V. P. Shah, K. K. Midha, S. Dighe et al., “Analytical methods validation: bioavailability, bioequivalence and pharmacokinetics studies,” International Journal of Pharmaceutics, vol. 82, no. 1-2, pp. 1–7, 1992. View at Publisher · View at Google Scholar · View at Scopus
  47. Food and Drug Administration, Guidance For Industry, Bioanalytical Methods Validation, US Food and Drug Administration, 2001.
  48. M. Feinberg and M. Laurentie, “A global approach to method validation and measurement uncertainty,” Accreditation and Quality Assurance, vol. 11, no. 1-2, pp. 3–9, 2006. View at Publisher · View at Google Scholar · View at Scopus
  49. W. C. Andersen, S. B. Turnipseed, C. M. Karbiwnyk et al., “Determination and confirmation of melamine residues in catfish, trout, tilapia, salmon, and shrimp by liquid chromatography with tandem mass spectrometry,” Journal of Agricultural and Food Chemistry, vol. 56, no. 12, pp. 4340–4347, 2008. View at Publisher · View at Google Scholar · View at Scopus
  50. R. L. Epstein, V. Randecker, P. Corrao, J. T. Keeton, and H. R. Cross, “Influence of heat and cure preservatives on residues of sulfamethazine, chloramphenicol, and cyromazine in muscle tissue,” Journal of Agricultural and Food Chemistry, vol. 36, no. 5, pp. 1009–1012, 1988. View at Google Scholar · View at Scopus
  51. D. N. Heller and C. B. Nochetto, “Simultaneous determination and confirmation of melamine and cyanuric acid in animal feed by zwitterionic hydrophilic interaction chromatography and tandem mass spectrometry,” Rapid Communications in Mass Spectrometry, vol. 22, no. 22, pp. 3624–3632, 2008. View at Publisher · View at Google Scholar · View at Scopus
  52. M. Lin, “A review of traditional and novel detection techniques for melamine and its analogues in foods and animal feed,” Frontiers of Chemical Engineering in China, vol. 3, no. 4, pp. 427–435, 2009. View at Publisher · View at Google Scholar · View at Scopus
  53. R. Muñiz-Valencia, S. G. Ceballos-Magaña, D. Rosales-Martinez et al., “Method development and validation for melamine and its derivatives in rice concentrates by liquid chromatography. Application to animal feed samples,” Analytical and Bioanalytical Chemistry, vol. 392, no. 3, pp. 523–531, 2008. View at Publisher · View at Google Scholar · View at Scopus
  54. T. Sugita, H. Ishiwata, K. Yoshihira, and A. Maekawa, “Determination of melamine and three hydrolytic products by liquid chromatography,” Bulletin of Environmental Contamination and Toxicology, vol. 44, no. 4, pp. 567–571, 1990. View at Publisher · View at Google Scholar · View at Scopus
  55. P. Varelis and R. Jeskelis, “Preparation of [13C3]-melamine and [13 C3]-cyanuric acid and their application to the analysis of melamine and cyanuric acid in meat and pet food using liquid chromatography-tandem mass spectrometry,” Food Additives and Contaminants A, vol. 25, no. 10, pp. 1208–1215, 2008. View at Publisher · View at Google Scholar · View at Scopus
  56. Y. Wang, H. Gu, X. Lu, and G. Xu, “Development of hydrophilic interaction chromatographic hyphenated techniques and their applications,” Se Pu, vol. 26, no. 6, pp. 752–754, 2008. View at Google Scholar
  57. R. Wei, R. Wang, Q. Zeng, M. Chen, and T. Liu, “High-performance liquid chromatographic method for the determination of cyromazine and melamine residues in milk and pork,” Journal of Chromatographic Science, vol. 47, no. 7, pp. 581–584, 2009. View at Google Scholar · View at Scopus
  58. X.-L. Zheng, B.-S. Yu, K.-X. Li, and Y.-N. Dai, “Determination of melamine in dairy products by HILIC-UV with NH2 column,” Food Control, vol. 23, no. 1, pp. 245–250, 2012. View at Publisher · View at Google Scholar · View at Scopus
  59. S. Huet, E. Jolivet, and A. Messean, Regression Non Lineare, INRA, Paris, France, 1992.
  60. Eurachem/Citac Guide, Quantifying the Uncertainty in Analytical Measurement, 2nd edition, 2000.
  61. JCGM 100:2008, Evaluation of measurement data—Guide to the expression of uncertainty in measurement (GUM), http://www.bipm.org/utils/common/documents/jcgm/JCGM_100_2008_E.pdf, 2008.