Synthesis of Pyrroloquinones via a CAN Mediated Oxidative Free Radical Reaction of 1,3-Dicarbonyl Compounds with Aminoquinones

Figure 4

CAN-mediated oxidative free radical cyclization reaction of benzylamino quinones yielding substituted N-benzyl pyrroloquinones. ^aisolated yields; *EtOH/CH₂Cl₂ mixture was used instead of MeOH/CH₂Cl₂ to avoid transesterification; ^†triple volume of solvents and heating was used to dissolve starting materials.