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Journal of Chemistry
Volume 2013, Article ID 312961, 5 pages
Research Article

Synthesis, Characterization, and Antimicrobial Activity of Methyl-2-aminopyridine-4-carboxylate Derivatives

1Department of Chemistry, Sri Jayachamarajendra College of Engineering, Manasagangotri, Mysore 570 006, India
2Postgraduate Department of Chemistry, JSS College of Arts, Commerce and Science, Ooty Road, Mysore 570 025, India

Received 1 June 2012; Revised 29 June 2012; Accepted 9 July 2012

Academic Editor: Hakan Arslan

Copyright © 2013 S. Nagashree et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A series of methyl-2-aminopyridine-4-carboxylate derivatives, 3a–f, were synthesized in order to determine their in vitro antimicrobial activity. The chemical structures of the synthesized compounds were confirmed by elemental analyses, FT-IR, and 1H NMR spectral studies. Among the synthesized compounds, 3c and 3d showed good antimicrobial activity compared to other compounds in the series.