Utility of Charge Transfer and Ion-Pair Complexation for Spectrophotometric Determination of Eletriptan Hydrobromide in Pure and Dosage Forms

Table 2

Statistical analysis for determination of ELT by the proposed methods.

Parameters	QUIZ	ARS	Mo(V)-thiocyanate
Wavelengths λ max (nm)	569	533	470
Beer’s law limits (μg mL^−1)	2.0–18	1.0–8.0	2.0–32
Molar absorptivity 𝜀, (L/mol^−1 cm^−1) × 10^4	1.1924	3.307	1.1886
Sandell’s sensitivity (ng cm^−2)	38.86	14..01	38.99
Regression equation^a
Slope (𝑏)	0.0264	0.0705	0.0262
Intercept (𝑎)	−0.0041	0.0004	−0.0033
Correlation coefficient (𝑟)	0.9994	0.9998	0.9998
Mean recovery % ± SD	100.21±0.927	99.74±0.836	99.79±0.862
RSD %	0.925	0.838	0.861
RE %	0.971	0.982	0.904
Variance	0.859	0.699	0.743
LOD, (µg mL^−1)^b	0.359	0.215	0.332
LOQ, (µg mL^−1)^b	1.20	0.717	1.11
Calculated t-value^c	0.5	0.30	0.207
Calculated F-value^c	1.09	1.35	1.27

aA= a + bC, where C is the concentration in μg mL⁻¹, A is the absorbance units, a is the intercept, and b is the slope.
bLOD: limit of detection; LOQ: limit of quantification; 𝜀: molar absorptivity.
cThe theoretical values of 𝑡 and 𝐹 are 2.57 and 5.05, respectively, at confidence limit at 95% confidence level and five degrees of freedom (P = 0.05).