Synthesis of Dextran/Methoxy Poly(ethylene glycol) Block Copolymer

Table 1

Characterization of the DexPEG block copolymer.

	Mn by ^1H-NMR	Molecular weight by GPC			Conjugation yield (%)
		Mn	Mw	Polydispersity	NMR^a
Dextran	—	14,390	16,950	1.177±0.054	—
Dextran-NH2	14,505	14,680	18,050	1.229±0.057	99.2
DexPEG	16,086	16,060	20,270	1.262±0.104	84.8

Mn: number-average molecular weight; Mw: weight-average molecular weight.
^aConjugation yield (CY) was evaluated by comparison of sum of proton peak (proton 1 position of dextran) of dextran and sum of proton peaks of hexamethylene diamine or mPEG.