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Journal of Chemistry
Volume 2013, Article ID 418969, 7 pages
Research Article

A Clean, Simple, and Efficient Synthesis of 2-Substituted Aryl (Indolyl) Kojic Acid Derivatives by Kaolin/Ag Nanocomposite as a Reusable Catalyst: A Green Protocol

Department of Chemistry, Islamic Azad University, Yazd Branch, P.O. Box 89195-155, Yazd 8916871967, Iran

Received 20 May 2013; Revised 23 July 2013; Accepted 24 July 2013

Academic Editor: Mallikarjuna Nadagouda

Copyright © 2013 Bahareh Sadeghi and Mohammad Reza Shahedi. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Kaolin/Ag nanocomposite (kaolin/Ag nanocomposite) was synthesized in a nanoreactor by the calcination of the precursor at high temperature and was shown to efficiently catalyze the one-pot, three-component reaction of an aromatic aldehyde, kojic acid, and indole derivatives under solvent-free conditions to afford the corresponding 2-substituted aryl (indolyl) kojic acid derivatives in high yield.