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Journal of Chemistry
Volume 2013, Article ID 429235, 5 pages
http://dx.doi.org/10.1155/2013/429235
Research Article

Cyanuric Chloride-Catalyzed Michael Addition of Indoles to Nitroolefins under Solvent-Free Conditions

1College of Chemistry and Chemical Engineering, Xinxiang University, Henan, Xinxiang 453003, China
2School of Pharmacy, Xinxiang Medical University, Henan, Xinxiang 453003, China

Received 28 June 2012; Accepted 27 July 2012

Academic Editor: Grégory Durand

Copyright © 2013 Xiao Juan Yang and Yun Jing. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Cyanuric chloride is an inexpensive, efficient, and mild catalyst for the Michael addition of indoles to nitroolefins at 70°C under solvent-free conditions. The simple experimental procedure, solvent-free reaction conditions, utilization of an inexpensive and readily available catalyst, short period of conversion, and excellent yields are the advantages of the present method.