Fabrication of Heparinized Mesoporous Silica Nanoparticles as Multifunctional Drug Carriers

Table 1

Structural parameters of MFMSNs, MFMSNs-HP, IDM-loaded MFMSNs-HP, and DOX-loaded MFMSNs-HP.

Sample	𝑉𝑝	𝑆BET	𝐷𝑝	Heparin loading	Indomethacin loading	DOX loading
	(cm^2/g)	(m^2/g)	(nm)	(wt%)	(wt%)	(wt%)
MFMSNs	0.33	502	2.65			0.1787
MFMSNs-HP	0.35	395	2.14	2
IDM-loaded MFMSNs-HP	0.35	383	2.13
DOX-loaded MFMSNs-HP	0.36	296	2.10			2.5

^aThe specific surface area (𝑆) was calculated by the BET equation. ^bThe pore volume (𝑉) was obtained according to BJH method. ^cThe pore size (𝐷) was calculated by the BJH method from N₂ desorption isotherms.