Synthesis and Biological Evaluation of New N,N′-Bis(1-substituted-ethylidene)-ethane1,2-diamine and Their Acetyl and Trifluoroacetyl Derivatives as Cytotoxic and Antimicrobial Agents

Table 6

Antibacterial and antifungal data of Schiff bases and their acyl derivatives (2–5) using UV (366) light.

Compound	Zone of inhibition in mm; Antibacterial activity		Zone of inhibition in mm; Antifungal activity
	Escherichia coli	Staphylococcus aureus	Aspergillus niger	Candida albicans
2a	13	—	14	13
2b	18	—	—	16
2c	—	17	—	—
2d	15	—	—	16
2e	16	—	—	16
2f	17	16	15	16
2g	19	17	17	15
2h	20	—	—	—
2i	14	16	—	—
2j	—	—	17	13
2k	—	14	—	—
3a	25	26	—	26
3b	—	—	—	—
3c	—	—	27	27
3d	29	28	29	—
3e	28	—	—	28
3f	—	—	—	—
3g	28	27	—	—
3h	30	28	26	—
3i	—	26	—	—
4a	20	17	21	19
4b	—	21	—	21
4c	—	17	—	—
5a	27	26	—	—
5b	—	25	—	—
Ampicillin	32	28	—	—
Griseofulvin	—	—	31	29