Exploring QSAR for Antimalarial Activities and Drug Distribution within Blood of a Series of 4-Aminoquinoline Drugs Using Genetic-MLR

Table 4

Data of the selected descriptors used in this study for 3D7 and W2 strains.

Log (1/IC50) 3D7	RDF020u	Mor06m	R8u+	Gu	HATS5u	Log (1/IC50) W2	RDF040m	H4u	MATS6m	Mor16u	Mor32v
−1.23	8.482	2.855	0.143	0.155	0.426	−2.58	8.088	1.518	1.019	−0.265	−0.057
−2.06	8.817	2.123	0.091	0.145	0.296	−2.43	2.966	2.046	1.007	−0.423	−0.322
−1.79	8.592	1.032	0.121	0.154	0.406	−2.46	2.441	1.788	1.021	0.034	−0.152
−1.71	8.680	1.334	0.128	0.153	0.397	−2.46	2.882	1.914	1.023	−0.175	−0.136
−1.16	8.878	2.716	0.117	0.154	0.366	−1.24	8.036	1.752	1.027	−0.464	0.012
−1.32	7.909	2.389	0.115	0.149	0.284	−1.54	10.184	2.005	1.013	−0.429	−0.311
−1.70	8.912	2.561	0.092	0.151	0.356	−1.70	12.780	1.882	1.018	−0.075	−0.006
−1.65	9.702	2.375	0.091	0.151	0.359	−1.85	10.177	1.887	1.021	0.073	−0.020
−0.30	12.872	2.769	0.093	0.153	0.328	−0.48	14.434	2.048	1.022	−0.018	−0.163
−1.80	10.114	2.523	0.085	0.150	0.433	−1.82	9.494	1.785	1.016	−0.405	−0.100
−0.70	11.126	3.597	0.077	0.156	0.345	−0.97	9.788	2.408	1.016	−0.335	−0.134
−0.78	9.626	3.510	0.121	0.149	0.295	−0.90	11.126	2.455	1.020	0.237	−0.292
−0.87	9.082	3.078	0.094	0.158	0.357	−1.04	13.566	1.859	1.024	−0.133	0.006
0.00	11.243	3.620	0.118	0.149	0.302	−0.59	9.226	2.530	1.011	−0.680	−0.291
−1.85	8.718	2.504	0.070	0.150	0.286	−2.00	8.821	2.107	1.015	0.258	−0.246
−0.91	10.266	3.272	0.077	0.150	0.267	−1.90	9.700	1.892	1.012	−0.391	−0.234
−1.11	11.035	2.470	0.078	0.153	0.328	−1.53	8.216	2.259	1.012	−0.047	−0.302
−0.70	11.287	2.756	0.092	0.147	0.242	−1.08	10.521	2.068	1.021	−0.106	−0.191
−0.40	14.060	3.062	0.108	0.153	0.401	−0.75	14.526	1.566	1.026	0.000	−0.170
−1.11	10.814	3.041	0.100	0.158	0.394	−2.26	8.180	2.092	1.012	−0.235	−0.154
−0.67	10.923	2.321	0.099	0.164	0.419	−1.66	8.161	1.855	1.020	−0.183	−0.164