Validation of Quetiapine Fumarate in Pharmaceutical Dosage by Reverse-Phase HPLC with Internal Standard Method

Table 1

System suitability study.

System suitability
	ISTD	Drug	T.P	Tailing	Resolution	P/A ratio	RT (ISTD)	RT (drug)
Inj-01	802777	557601	5485	1.25	10.21	0.695	1.45	3.62
Inj-02	796543	564024	5449	1.25	10.23	0.708	1.45	3.63
Inj-03	788450	542945	5566	1.25	10.37	0.689	1.44	3.63
Inj-04	773744	545361	5619	1.25	10.43	0.705	1.44	3.62
Inj-05	787322	543398	5587	1.25	10.32	0.690	1.44	3.62
Inj-06	791033	551887	5457	1.25	10.28	0.698	1.44	3.62
Mean	789978	550869	5527	1.25	10.3067	0.697334	1.443	3.623
S.D	9807.74	8583.17	72.57	0.00	0.0841	0.00783	0.005	0.005
RSD	1.24	1.56	1.31	0.00	0.8156	1.122889	0.358	0.143