Journal of Chemistry / 2013 / Article / Tab 1

Research Article

A Green and Efficient Method for the Preparation of 3,4-Dihydropyrimidin-2(1H)-ones Using Quaternary Ammonium-Treated Clay in Water

Table 1

Optimization of experimental conditions for synthesis of DHPMs.

EntryCatalystTemperatureTime (h)Result

1CTAB-modified clay (0.02 g)
Reflux 0.5 Not completed, 44% yield
2CTAB-modified clay (0.04 g)
Reflux 0.5 Not completed, 77% yield
3CTAB-modified clay (0.05 g)
Reflux 0.5 Completed, 89% yield
4CTAB-modified clay (0.05 g)
r.t0.5 Not completed, 35% yield
5ClayReflux 0.5 No reaction

Reaction conditions: benzaldehyde (1 mmol), acetylacetone (1 mmol), and urea (1.5 mmol).