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Journal of Chemistry
Volume 2013, Article ID 636280, 7 pages
Research Article

Alkylation and 1,3-Dipolar Cycloaddition of 6-Styryl-4,5-dihydro-2H-pyridazin-3-one: Synthesis of Novel N-Substituted Pyridazinones and Triazolo[4,3-b]pyridazinones

1Laboratoire de Chimie Organique et Analytique, Faculté des Sciences et Techniques, Université Sultan Moulay Slimane, BP 523, Béni-Mellal, Morocco
2Department of Chemistry and QOPNA, University of Aveiro, 3810-193 Aveiro, Portugal
3Laboratoire de Diffraction des Rayons X, Centre Nationale pour la Recherche, Scientifique et Technique, Rabat, Morocco

Received 9 June 2012; Accepted 18 September 2012

Academic Editor: Julia Revuelta

Copyright © 2013 Souad Mojahidi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Some new N-substituted pyridazinones and triazolo[4,3-b]pyridazinones were synthesized, respectively, by simple alkylation and 1,3-dipolar cycloaddition of pyridazin-3-one with nitrile imines. The regioselectivity of the reactions was ascertained by 1H, 13C NMR spectroscopy and X-ray diffraction of the synthesized compounds.