Biophysical and RNA Interference Inhibitory Properties of Oligonucleotides Carrying Tetrathiafulvalene Groups at Terminal Positions

Table 1

Sequences of DNA and RNA oligonucleotides.

No.	Sequence (5′-3′)(a)
1	TAG AGG CTC CAT TGC
2	GCA ATG GAG CCT CTA
3	TAG AGG CTC CAT TGC-TTF1
4	GCA ATG GAG CCT CTA-TTF1
5	TTF1-GCA ATG GAG CCT CTA
6	TAG AGG CTC CAT TGC-PYR
7	TAG AGG CTC CAT TGC-PFP
8	CGC GAA TTC GCG
9	CGC GAA TTC GCG-PYR
10	CGC GAA TTC GCG-PFP
11	auc uga aga agg aga aaa aTT
12	uuu uuc ucc uuc uuc aga uTT
13	gcu aca gag aaa ucu cga uTT
14	auc gag auu ucu cug uag cTT
15	auc uga aga agg aga aaa aTT-TTF2
16	uuu uuc ucc uuc uuc aga uTT-TTF2

^(a)TTF: tetrathiafulvalene, PYR: pyrene, PFP: 2,3,4,5,6-pentafluorophenyl.
Base notation: DNA = A, C, and G; and T. RNA = a, g, c, and u.