Research Article

Validated HPTLC Method for Simultaneous Analysis of Pyrimethamine and Sulphadoxine in Pharmaceutical Dosage Forms

Table 2

Intraday and interday precision data for PYR and SUL ( ).

DrugQuantityIntraday precisionInterday precision
(ng) per bandMean R.R.F ± SDRSD (%)Mean R.R.F ± SDRSD (%)

PYR1000.123 ± 0.00120.980.142 ± 0.00211.47
2000.171 ± 0.00140.820.194 ± 0.00190.98
3000.241 ± 0.00130.540.254 ± 0.00230.91

SUL20001.152 ± 0.01411.221.172 ± 0.02141.83
30001.253 ± 0.01250.991.260 ± 0.02071.64
40001.421 ± 0.01350.951.443 ± 0.02311.60

PYR: pyrimethamine; SUL: sulphadoxine.