Research Article
Validated HPTLC Method for Simultaneous Analysis of Pyrimethamine and Sulphadoxine in Pharmaceutical Dosage Forms
Table 2
Intraday and interday precision data for PYR and SUL (
).
| Drug | Quantity | Intraday precision | Interday precision | (ng) per band | Mean R.R.F ± SD | RSD (%) | Mean R.R.F ± SD | RSD (%) |
| PYR | 100 | 0.123 ± 0.0012 | 0.98 | 0.142 ± 0.0021 | 1.47 | 200 | 0.171 ± 0.0014 | 0.82 | 0.194 ± 0.0019 | 0.98 | 300 | 0.241 ± 0.0013 | 0.54 | 0.254 ± 0.0023 | 0.91 |
| SUL | 2000 | 1.152 ± 0.0141 | 1.22 | 1.172 ± 0.0214 | 1.83 | 3000 | 1.253 ± 0.0125 | 0.99 | 1.260 ± 0.0207 | 1.64 | 4000 | 1.421 ± 0.0135 | 0.95 | 1.443 ± 0.0231 | 1.60 |
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PYR: pyrimethamine; SUL: sulphadoxine.
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