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Journal of Chemistry
Volume 2013, Article ID 718937, 9 pages
Research Article

Synthesis Antioxidant and Antimicrobial Activities of N-[(5′-Substituted 2′-phenyl-1H-indol-3′-yl)methylene]-5-(pyridin-4-yl)-1,3,4-oxadiazol-2-amines

1Department of Post-Graduate Studies and Research in Chemistry, Gulbarga University, Gulbarga Karnataka 585 106, India
2Shri Prabhu Arts, Science and J. M. Bohra, Commerce Degree College, Shorapur Karnataka 585 224, India

Received 30 June 2012; Accepted 30 November 2012

Academic Editor: Antonio J. Melendez-Martinez

Copyright © 2013 A. R. Saundane et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The main aim of the present study was to develop antimicrobial and antioxidant compounds. As a part of systematic investigation, several new compounds 3a–c, 4a–c, and 5a–f were synthesized and screened for their biological activities. Compound 5f showed good zone of inhibition versus E. coli, S. aureus, and K. pneumoniae, whereas the compound 3a showed promising radical scavenging activity, ferric ions (Fe3+) reducing antioxidant power, and ferrous ions (Fe2+) metal chelating activity.