Research Article
Synthesis Antioxidant and Antimicrobial Activities of N-[(5′-Substituted 2′-phenyl-1H-indol-3′-yl)methylene]-5-(pyridin-4-yl)-1,3,4-oxadiazol-2-amines
Table 1
Antibacterial activity of compounds 3–5.
| Comp. number | Conc. (μg/mL) (zone of inhibition in mm) | E. coli | S. aureus | K. pneumoniae | P. aeruginosa | 1000 | 750 | 500 | 1000 | 750 | 500 | 1000 | 750 | 500 | 1000 | 750 | 500 |
| 3a | 10 | 10 | 11 | 12 | 12 | 12 | 05 | 05 | 08 | 09 | 09 | 09 | 3b | 05 | 05 | 08 | 09 | 09 | 10 | 02 | 02 | 05 | 05 | 05 | 08 | 3c | 08 | 08 | 10 | 05 | 05 | 07 | 10 | 10 | 11 | 11 | 11 | 10 | 4a | 13 | 13 | 14 | 09 | 09 | 10 | 09 | 10 | 10 | 02 | 02 | 05 | 4b | 09 | 09 | 10 | 05 | 05 | 08 | 10 | 05 | 06 | 10 | 10 | 11 | 4c | 10 | 10 | 11 | 02 | 02 | 05 | 09 | 09 | 10 | 11 | 11 | 10 | 5a | 09 | 11 | 11 | 07 | 07 | 09 | 09 | 09 | 10 | 09 | 10 | 11 | 5b | 11 | 03 | 05 | 00 | 00 | 00 | 05 | 05 | 06 | 14 | 13 | 12 | 5c | 09 | 09 | 09 | 04 | 04 | 06 | 05 | 09 | 10 | 02 | 02 | 05 | 5d | 14 | 14 | 14 | 12 | 12 | 12 | 10 | 10 | 12 | 13 | 13 | 13 | 5e | 14 | 14 | 14 | 09 | 09 | 12 | 09 | 10 | 10 | 13 | 13 | 13 | 5f | 13 | 13 | 14 | 16 | 14 | 13 | 13 | 13 | 13 | 05 | 06 | 08 |
| Std. | 16 | 16 | 15 | 18 | 16 | 15 | 15 | 15 | 14 | 15 | 14 | 14 |
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Std.: Streptomycin (Standard).
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