Design, Synthesis, and In Vitro Antioxidant Activity of 1,3,5-Trisubstituted-2-pyrazolines Derivatives

Table 3

Free radical scavenging activity of 5-furan-2-yl-3-aryl-4, 5-dihydro-1H-pyrazole 2(a–e).

Compound	Concentration in μg/mL	Percentage of scavenging ± SD
		DPPH	Nitric oxide
2a	500	14.65±0.324	61.06±0.983
	250	06.32±1.619	41.01±1.280
	125	05.66±0.081	31.05±1.367
2b	500	13.34±0.371	42.51±0.923
	250	07.81±1.194	22.85±0.976
2c	500	14.46±1.425	30.98±0.596
	250	09.03±0.493	26.23±0.298
2d	500	69.00±0.986	67.25±0.491
	250	68.39±1.857	59.30±0.406
	125	69.66±0.854	55.79±0.491
	62.5	46.20±1.582	41.79±0.390
2e	500	74.34±0.902	59.24±0.112
	250	75.09±1.054	49.93±0.298
	125	64.84±0.773	40.82±0.516
	62.5	51.63±1.475	33.00±0.516
	31.25	21.91±1.114	—
Ascorbic acid	50	50±0.16	—
Rutine	50	70±0.16	50±0.11