Design, Synthesis, and In Vitro Antioxidant Activity of 1,3,5-Trisubstituted-2-pyrazolines Derivatives

Table 4

Free radical scavenging activity of 5-furan-2-yl-3-aryl-1-[(3-chloro-phenyl) methyl amino]-2-pyrazoline 3(a–e).

Compound	Concentration in μg/mL	Percentage of scavenging ± SD
		DPPH	Nitric oxide
3a	500	57.16±0.612	70.72±0.331
	250	36.23±0.506	63.60±0.315
	125	18.82±1.264	60.88±0.103
	62.5	09.59±0.858	56.38±0.259
3b	500	18.58±1.615	32.37±0.630
	250	07.16±2.189	29.23±0.622
3c	500	04.63±0.643	16.47±0.930
3d	500	48.50±1.501	52.35±0.157
	250	32.06±1.778	46.43±0.103
	125	19.56±0.996	43.99±0.214
3e	500	85.06±0.663	89.02±0.487
	250	87.92±0.612	91.12±0.449
	125	85.95±1.224	89.68±0.899
	62.5	61.84±1.733	71.96±1.273
	31.25	37.26±0.214	53.90±0.157
Ascorbic acid	50	50±0.16	—
Rutine	50	70±0.16	50±0.11