Journal of Chemistry / 2013 / Article / Tab 4

Research Article

Development and Validation of HLPC Method for the Estimation of Lamotrigine in Bulk and Pharmaceutical Formulations

Table 4

Study of robustness of the proposed method.

S. no.Flow rate mL/min.Plate countTailing factor% mobile phasePlate countTailing factor

10.62573.01.610% less2250.91.6
20.72365.71.5Actual2365.71.5
30.82461.11.510% high2166.31.5

R e s u l t s for actual flow (0.7 mL/min) have been considered from assay standard.
R e s u l t s for actual mobile phase composition (60 : 40 acetonitrile : buffer) have been considered.

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