C-Glycosidic Genistein Conjugates and Their Antiproliferative Activity

Figure 2

Morphology of HCT 116 cells treated with C-glycoconjugates of genistein for 24 h. (a), (b) Non-treated control; (c), (d) 5 μM 3a; (e), (f) 20 μM 3f. ((a), (c), and (e) DIC contrast; (b), (d), and (f) confocal images of cells stained with Hoechst 33342, Lysotracker red, and Mitotracker green). Circles in (d) and (f) mark apoptotic cells, arrows indicate cell with fragmented nuclei or with large micronuclei. Scale bar: 40 μm in left panel ((a), (c), and (e)); 20 μm in the right panel ((b), (d), and (f)).

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