Studies on the Identification of Constituents in Ethanol Extract of Radix Glycyrrhizae and Their Anti-Primary Hepatoma Cell Susceptibility

Table 2

Effects of various drugs on cell cycle phases of primary hepatoma cells (𝑥±𝑠, %).

Group	Concentration (μg/mL)	G0/G1	𝑃 value	S	𝑃 value	G2/M	𝑃 value
Control group	0	26.7±4.3		68.5±3.2		5.8±1.3
5-FU group	10	58.7±3.6	<0.01	26.7±3.2	<0.01	14.3±3.2	<0.05
Liquiritigenin group	100	55.9±4.1	<0.01	28.7±1.2	<0.01	14.8±0.3	<0.05
Liquiritin group	100	39.8±2.3	<0.05	49.2±1.1	<0.05	11.2±0.6	<0.05
Isoliquiritigenin group	100	38.5±3.1	<0.05	49.3±1.5	<0.05	12.3±0.4	<0.05
Betulinic acid group	100	30.7±3.2	—	63.5±2.0	—	6.5±0.6	—
Oleanolic acid group	100	28.5±3.1	—	64.6±1.6	—	6.8±0.2	—