Research Article

Synthesis, Single Crystal X-Ray Structure, and Antimicrobial Activity of 6-(1,3-Benzodioxol-5-ylmethyl)-5-ethyl-2-{[2-(morpholin-4-yl)ethyl]sulfanyl}pyrimidin-4(3H)-one

Table 4

Diameter of growth inhibition zone (mm) of the target compound 8, ampicillin, and clotrimazole towards the test microorganisms.

Compound numberDiameter of growth inhibition zone ± SD (mm)*
Gram-positive bacteria Pathogenic fungi
Staphylococcus aureus Bacillus subtilis Bacillus cereus Candida albicans Aspergillus niger

820 ± 0.5018 ± 1.0019 ± 1.5017 ± 1.5020 ± 1.50
Ampicillin32 ± 1.0028 ± 1.0027 ± 0.50
Clotrimazole35 ± 1.0032 ± 0.00

The arithmetic mean of the inhibition zone diameters in mean ± standard deviation in mm.