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Journal of Chemistry
Volume 2014, Article ID 563406, 21 pages
Review Article

Pharmacological Profile of Quinoxalinone

1Laboratoire National de Contrôle des Médicaments, D M P, Ministère de la Santé, Madinat Al Irnane, BP 6206, Rabat, Morocco
2Unité de la Radioimmunoanalyse, Centre National d’Etudes Scientifiques et Techniques d’Energie Nucléaire, BP 1382, Rabat, Morocco
3Laboratoire de Chimie Thérapeutique, Faculté de Médecine et de Pharmacie de Rabat-Souissi, Université Mohamed V, BP 6203, Rabat, Morocco
4Laboratoire de Chimie Organique Hétérocyclique, RAC 21, Université Mohammed V-Agdal, Rabat, Morocco

Received 19 May 2013; Accepted 22 October 2013; Published 9 February 2014

Academic Editor: Marc Visseaux

Copyright © 2014 Youssef Ramli et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Quinoxalinone and its derivatives are used in organic synthesis for building natural and designed synthetic compounds and they have been frequently utilized as suitable skeletons for the design of biologically active compound. This review covers updated information on the most active quinoxalinone derivatives that have been reported to show considerable pharmacological actions such as antimicrobial, anti-inflammatory, antidiabetic, antiviral, antitumor, and antitubercular activity. It can act as an important tool for chemists to develop newer quinoxalinone derivatives that may prove to be better agents in terms of efficacy and safety.