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Journal of Chemistry
Volume 2014 (2014), Article ID 728254, 9 pages
Research Article

Prediction and Evaluation of the Mixture Toxicity of Twelve Phenols and Ten Anilines to the Freshwater Photobacterium Vibrio qinghaiensis sp.-Q67

College of Environmental Science and Engineering, Guilin University of Technology, Guilin 541004, China

Received 18 April 2014; Revised 1 July 2014; Accepted 1 July 2014; Published 16 July 2014

Academic Editor: Maria N. D.S. Cordeiro

Copyright © 2014 Lingyun Mo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Twelve substituted phenols and ten substituted anilines were chosen to investigate if the dose addition and independent action models can be used to evaluate the mixture toxicity of phenolic and aniline derivatives (PADs). Their photobacterium toxicity to the freshwater luminescent bacterium Vibrio qinghaiensis sp.-Q67 showed that the two-parameter Weibull or Logit function could be effectively applied to describe the dose-response relationships. The joint toxicity of three equivalent-effect concentration ratio (EECR) mixtures and twelve uniform design concentration ratio (UDCR) mixtures could be well evaluated using the dose addition (DA) or the independent action (IA) model within 95% confidence intervals.