Synthesis of Some New Pyrimidine-Azitidinone Analogues and Their Antioxidant, In Vitro Antimicrobial, and Antitubercular Activities

Table 3

The in vitro antioxidant activity of 7a–j in nitric oxide (NO) method.

Compound	Concentration (µg/mL)
	25	50	75	IC50
7a	71.23±0.85	74.85±1.08	77.13±1.43	17.55±0.96
7b	68.34±0.95	70.61±1.39	74.18±0.95	18.27±1.05
7c	72.90±0.85	74.06±0.94	78.25±1.06	17.14±0.56
7d	64.37±1.18	69.22±1.57	74.69±1.41	19.45±1.27
7e	53.64±1.39	56.49±1.24	60.03±0.71	23.35±1.14
7f	62.04±1.41	66.83±1.56	70.92±0.78	20.15±0.98
7g	59.95±1.55	60.47±1.21	62.56±1.31	20.49±0.94
7h	73.03±0.23	78.14±0.45	82.44±0.62	17.15±0.95
7i	71.84±0.17	76.29±0.35	79.65±0.54	17.39±1.15
7j	75.23±0.26	79.53±0.37	82.64±0.57	16.65±0.60
Ascorbic acid	84.72±0.18	85.96±0.36	88.32±0.52	14.71±0.54
Blank	—	—	—	—

(—) showed no scavenging activity. Values were the means of three replicates ± SD.