Research Article

Synthesis of Some New Pyrimidine-Azitidinone Analogues and Their Antioxidant, In Vitro Antimicrobial, and Antitubercular Activities

Table 6

Antituberculosis activity of pyrimidine derivatives.

CompoundInhibition (%)MIC (lg/mL)
M. tuberculosis (H37Rv)

7a58>6.25
7b59>6.25
7c67>6.25
7d58>6.25
7e72>6.25
7f68>6.25
7g71>6.25
7h82>6.25
7i806.25
7j956.25
Rifampicin ā€”0.125
Isoniazid ā€”0.05