Review Article

Current Uses of Poly(lactic-co-glycolic acid) in the Dental Field: A Comprehensive Review

Table 2

Applications of PLGA scaffolds in dentistry.

Type of PLGA scaffoldAdditional substances ApplicationStudy

PLGABMP-2
(bone morphogenetic protein-2)
Bone regeneration around dental implants[41]
PLGAPEG1
(prostaglandin E1)
Alveolar ridge preservation/augmentation[44]
PLGASimvastatinBone formation in extraction sockets[42]
PLGA-gelatin spongerhBMP-2
(recombinant human bone morphogenetic protein-2)
Alveolar ridge augmentation[46]
PLGA/calcium phosphate cementBone ingrowth[52]
PLGA + autogenous bone graftBone regeneration around implants[40]
PLGA/low crystalline apatiteBone regeneration[53]

PLGA/calcium phosphatesMaintaining alveolar bone height/augmenting alveolar bone height through standard sinus lift approaches[28]
PLGA + beta-tricalcium phosphate Bone and cementum regeneration[55]
PLGA/CaP (calcium phosphate) Periodontal regeneration of class II furcation defects[50]
PLGA + bone allograftrhBMP-2
(osteoinductive protein)
Alveolar ridge augmentation[43]
PLGASimvastatin and
SDF-1α
(stromal cell derived factor-1α)
Bone regeneration[45]
PLGA/β-tricalcium phosphateFibroblast growth factor-2Bone augmentation[54]