Review Article

Current Uses of Poly(lactic-co-glycolic acid) in the Dental Field: A Comprehensive Review

Table 3

Applications of PLGA scaffolds in regenerative dentistry.

Type of PLGA scaffoldsCells seeded on scaffoldsApplicationStudy

PLGA + calcium phosphate Bone marrow derived cells Bone formation[116]
PLGAOsteoblast cellsMaxillary sinus augmentation[56]
PLGABone marrow stem cellsBone regeneration[57]
PLGA + calcium phosphate Bone marrow stem cellsBone regeneration[47]
PLGA + nanohydroxyapatiteTooth bud cellsCell proliferation and differentiation[60]
PLGA/hydroxyapatiteDental pulp stem cellsOsteoblastic differentiation[59]
PLGA/hydroxyapatiteDedifferentiated fat cellsBony defects closure[61]
PLGA nanofibers Dental pulp stem cellsBone regeneration[58]
PLGAAdipose-derived stromal cells Regeneration of bone, periodontal ligament and cementum[66]
PLGADental pulp stem cells Dentine/pulp-like tissue[64]
PLGA Dental pulp stem cells Dentine-like structure [63]
PLGA + tricalcium phosphate Tooth bud cellsDentin-like and
pulp-like tissues
[65]
PLGA + CCN3
(nephroblastoma overexpressed)
Dental pulp stem cells Dentinogenesis[62]